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Timing is Everything: Using Chronotherapy in Cancer Treatment

Nov 03 by Ewcopywriting Leave a Comment

Cancer is one of the most deadly diseases in the world, killing an estimated 7.6 million people every year. While there is a constant flow of new treatments, the number of deaths nonetheless demands more research and, hopefully, an eventual cure. Many people use all available treatments but still die of this disease. For many, the treatment itself is part of the problem, as chemotherapy side effects can be quite serious. Until there are ways of stopping cancer in its tracks, we may be able to improve outcomes and reduce the tide of deaths by using chronotherapy in cancer treatment.

What Is Chronotherapy?

Every cell in our bodies runs on an internal clock called a circadian rhythm. Chronotherapy is the practice of timing treatments so they are taken at the most effective time of day. Giving medications at the right time can increase efficacy while reducing the actual amount of medication that patients need. For example, if a person who has high blood pressure primarily at night takes their medication before bed, not only will it be more effective, they will also need less medication than if they took it in the morning or another random time of day. This, in turn, reduces side effects, medication interactions and the chances of developing toxicity from high levels of medication.

We do not currently know all of the diseases that respond best to chronotherapy. However, research suggests that allergies, heart disease and a wide range of illnesses may be treated more effectively when treatments are given at specific times. According to new research on chronotherapy in cancer treatment, chemotherapy may be among the growing number of medications where timing is everything.

Using Chronotherapy in Cancer Treatment

Chemotherapy aims to kill cancer cells, but unfortunately kills many of the patient’s healthy cells as well. Balancing side effects and toxicity is a major challenge for both doctors and patients. What if there were a way to increase the efficacy of chemotherapy while decreasing side effects and toxicity? It appears that chronotherapy may be the answer.

A recent study found that chemotherapy and other cancer treatments are more effective when timed to coincide with the most active times of the circadian rhythm of cancer cells. In other words, timing the medications to stop growth exactly when the tumor is actively trying to grow. This study did not discover only a small difference in efficacy; the chemotherapy administered at the right time of day was actually twice as effective in treating cancer. The perfect time to give a drug depends on the type of cancer and the type of medication, but there appears to be a perfect time for most cancer drugs. Giving medications at carefully-determined times also reduces side effects and toxicity, which are two major reasons that patients often cannot continue with an otherwise successful treatment.

The Circadian Rhythm of Cancer Cells

Timing is Everything: Using Chronotherapy in Cancer TreatmentHow can timing the administration of a drug make such a difference? Cancer cells tend to have a circadian rhythm that is different from that of healthy cells. They have often lost many of the checkpoints to growth that are present in healthy cells, which means that they can grow almost continuously. While they may grow faster at certain times of day, they are growing or preparing to do so almost constantly. On the other hand, human cells grow only for very small periods of time during the day.

With many types of cancer, it is possible to identify a time when cancer cells are extremely active while normal cells are not. When a drug attacking that part of the cell cycle is administered at these times, it is likely to have a huge impact on cancer while affecting normal cells very little, which means fewer side effects.

Your Circadian Rhythm and Your Health

While most people are not aware of their circadian rhythm, your internal clock plays a huge role in your health. The amount you sleep—or don’t—can affect whether you feel rested but also your risk of developing serious diseases. Because a poorly-regulated circadian rhythm is essential to health, it makes sense that working with your own innate timing would play a role in recovery from serious diseases such as cancer.

If you or a loved one are facing a battle with cancer, chronotherapy may give you an advantage. It’s important to talk to your doctors about the best time to take your medications to maximize treatment and reduce adverse effects.

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Filed Under: Cellular Health, Chronobiology, Chronotherapy, Circadian Rhythm, Men's Health, Women's Health

Turning the Clocks Back This Weekend Could Be Detrimental to Your Health

Oct 31 by Ewcopywriting Leave a Comment

Couldn’t most of us use an extra hour of sleep? Many people look forward to the fall time change, which occurs on November 6 this year. Unlike the spring changing of the clocks, which equates to lost sleep, turning the clocks back in the fall, or “falling back,” gives us a much-needed extra hour of slumber. It also means waking up to a little more sunshine, even if we pay for that sunshine with an earlier sunset. However, the fall time change can impact your health in a variety of negative ways.

The History of Daylight Saving Time

Turning the Clocks Back This Weekend Could Be Detrimental to Your HealthThe tradition of turning the clocks back in the fall and forward in the spring began in World War II. Seasonally adjusting the clock in this way allowed people to enjoy maximum sunlight during the day, thus lowering the amount of resources used in lighting homes and businesses. Fuel was at a premium during the war, so this tactic had a measurable impact on how much fuel citizens used. When the war ended, the United States and Europe made Daylight Saving Time (DST) a local option.

Some communities continued the twice-yearly change in clocks while others did not. As the country became more mobile and well-connected, this inconsistency led to a great deal of confusion. This spurred the creation of the Uniform Time Act of 1966, which made changing clocks mandatory for the entire nation (except in the case of special exemptions). Since then, most Americans and a great deal of Europe as well changed clocks one hour forward in spring and one hour backward in the autumn.

The Effects of Time Change on Your Circadian Rhythm

Our bodies run according to a series of internal clocks known as our circadian rhythm. When our sleep-wake cycle changes suddenly, we suffer from the mixture of fatigue and clouded thinking that we call jet lag. Our bodies are suddenly out of sync with our environments and must adjust to the new time, a process that happens slowly.

In the spring, a switch to Daylight Saving Time means that many people lose an hour of sleep and must adjust to waking up significantly earlier. The effects of this change in time have been well-documented, including an increase in strokes, heart attacks and even car accidents. Until recently, much of the research on the effects of time change has centered on the spring change in clocks, as this involves losing sleep. However, it has become increasingly evident that the fall time change may also have a variety of negative effects on your health.

How Is Turning the Clocks Back Bad for Your Health?

While getting an extra hour of sleep is better than losing one, it still has an effect on the circadian rhythm. Many scientists believe that any change in the circadian rhythm can have long-term effects on health, including an increase in cancer risk. The decrease in light during the day also can have an effect on health. Children are less likely to play outside during the long dark hours of winter evenings, increasing the risk of obesity and the many other health risks associated with it. Adults are similarly less likely to go for a jog or otherwise get exercise when it’s dark out.

In addition, the decrease in light during waking hours can affect mental health, worsening mood disorders and increasing depression. Many people are affected mentally by a change in light, even among those who haven’t been diagnosed with seasonal affective disorder (SAD). We rely on light to regulate our circadian rhythms. A lack of light can throw metabolism into disarray and disrupt the internal clocks.

Healthy Ways to Deal With a Time Change

If you are concerned about how turning back the clocks affects your health, there are a few things you can do to soften the blow. Begin by slowly changing your schedule in the week before the time change, so it has a less-abrupt effect on your sleep-wake cycle. Maximize outdoor time and access to sunlight, even adding light therapy if you feel you can’t get enough sunshine. Take a melatonin supplement before bedtime if you aren’t feeling sleepy. Last, be sure to get enough exercise even if this means switching to indoor activities. Caring for your health and replacing the light stolen from your day can mitigate many of the effects of turning the clocks back.

Our circadian rhythms are essential to our health and well-being. There are many ill effects, both short-term and long-term, when we disrupt our internal clocks. However, there are ways to make Daylight Saving Time easier on our bodies and minds. Caring for your circadian rhythm is an important part of leading a healthy lifestyle.

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Filed Under: Chronobiology, Circadian Rhythm, Melatonin, Men's Health, Metabolism, Sleep, Women's Health

Health Dangers of Smartphones Include Insomnia and Male Infertility

Oct 27 by Ewcopywriting Leave a Comment

Unless you live under that proverbial rock, you are likely familiar with the purported health dangers of smartphones. Although these devices make it easier to manage our busy lives and stay in contact with loved ones, more and more studies indicate that they may also pose health risks, even when not in use.

The Effects of Electromagnetic Radiation

Even when your phone is not in use, it’s still in contact with cellphone towers. It maintains this contact using a frequency known as electromagnetic radiation, allowing your phone to make its distinctive chime as soon as you receive a text or email. Electromagnetic radiation is very similar to microwaves. There have been conflicting studies regarding whether this type of radiation affects your health, but more recent research shows that the suspected health dangers of smartphones are likely a reality.

Exactly what are these health effects? Rats exposed to constant levels of this frequency of radiation develop brain tumors. There are also specific dangers for men who keep cellphones on their person or in a pocket, including infertility and potential testicular cancer. While our brains are partially protected by a skull, male reproductive organs have few defenses against the electromagnetic radiation, which can mutate sperm and make them unable to fertilize an egg. This is particularly unfortunate when you consider how many men keep their cellphone in their pants pocket.

Smart Phones and Sleep

Health Dangers of Smart Phones Include Insomnia and Male InfertilitySmartphones can affect not just our long-term health, but our daily lives. They emit a blue-tinted light that is easy to read in almost any setting, much like computers and tablets. However, this light can affect our circadian rhythms and make it more difficult to get the sleep we need. Blue light has a huge effect on melatonin production, and can even shut it down completely. When you read on your smartphone or another device before bed, you are stopping your brain from making the hormone it needs to induce sleep. This is especially true for adolescents.

However, blue light is not the only way that a smartphone may interfere with your sleep. Electromagnetic radiation also may interfere with sleep. Children appear to be more affected, as their growing brain tissues absorb four times as much of this radiation as adults. In addition, children often lack the self-discipline needed to turn off these devices and go to sleep. It is important for children to go to sleep in a room free of televisions, tablets and other devices that could have long-term effects on both their circadian rhythm and whole-body health.

Mitigating the Health Dangers of Smartphones

This news may be shocking to people who always have their phone in hand. However, most of us either cannot or will not eschew our electronic devices completely. We need them not just for work and time management, but for much-needed recreation and fun. If you plan on keeping your smartphone in your pocket despite these health dangers, there are a few ways that you can lessen the potential damage to your body.

  • Use a headset or speakerphone. Moving a source of radiation away from your body significantly reduces its effect on your cells.
  • Keep your phone out of your pants pocket. Stash it instead in a bag, on your desk, or in a shirt pocket.
  • Don’t sleep with devices in your bedroom. Smart phones are not the only sources of radiation; wireless modems and other devices also emit it. By keeping these in another room, you can reduce your exposure immensely.
  • Avoid using your phone when it has a low signal. It has to send out more radiation to continue making contact.
  • Limit your children’s usage of devices. Children are especially prone to negative effects from radiation because their bodies are still growing and their cells multiplying quickly.

It may be difficult to break the smartphone habit, but it will likely have a beneficial effect on your health. There are many ways to reduce the health dangers of smartphones, but simply putting it away may be the most effective.

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Filed Under: Cellular Health, Chronobiology, Circadian Rhythm, Melatonin, Men's Fertility, Men's Health, Sleep

New Research Shows the Health Benefits of Resveratrol Extend Beyond Heart Health

Oct 13 by Ewcopywriting Leave a Comment

Resveratrol has been in the news for its heart-health benefits for years. It is believed to help support a healthy cardiovascular system and protect against a wide variety of  health concerns. New research on the health benefits of resveratrol suggests that, aside from its benefits to cardiovascular health, resveratrol may benefit your entire body through a mechanism that supports the healthy cellular inflammatory processes that are often thrown out of whack by our stressful modern life.

The Health Benefits of Resveratrol

Resveratrol is a plant compound found in grapes and red wine, as well as some nuts and berries. It is a natural antioxidant made by plants when they are under attack, whether from an insect or an illness. Although the foods containing this micronutrient are delicious, most people in the Western world do not get enough of it in their diets. This is unfortunate, because people who don’t get enough resveratrol may be missing out on some incredible health benefits.

New Research Shows the Health Benefits of Resveratrol Extend Beyond Heart HealthDoctors have long known that supplementing with this natural plant compound can help to protect against certain cardiovascular concerns which can eventually lead to devastating heart attack or stroke. In addition, it can help support healthy cellular inflammatory processes in your body. This can affect your health in a variety of ways because inflammation is often a hidden contributor to many of the most common and most-feared illnesses of our times.

What’s the Big Deal With Inflammation?

Many people associate inflammation with an infection, but it actually can be present even without microorganisms or viruses. In fact, new research suggests that inflammation may be a major cause of almost every type of disease in the human body. Chronic low-grade inflammation is one cause of atherosclerosis and thus heart disease and stroke. However, it also may contribute to the development of diabetes, cancer, and chronic diseases of all kinds.

How can inflammation cause so much damage? When our bodies suffer an insult of any kind, be it a microbe or a toxic food preservative, it sets off a reaction. There is more blood flow to the area, more inflammatory molecules and more immune cells such as T-cells. These cells can help to fight off an infection, but when they are chronically present they damage our own cells. Chronic inflammation can be so subtle it is missed entirely until we begin to develop chronic illness. In the case of atherosclerosis, the vessel gradually hardens because of the constant inflammation, the way our feet and hands can form calluses. These rough spots on the inside of the vessel are prone to cracking and also clot formation. Eventually, the atherosclerosis is enough to completely block the vessel, which is when disease occurs.

Protecting Against Inflammation the Natural Way

New Research Shows the Health Benefits of Resveratrol Extend Beyond Heart Health 1There are many ways that you can change your lifestyle to reduce the occurrence of inflammation and thus help protect against the diseases that it can cause. Eating a diet rich in fruits, vegetables and omega-3 fish oils is a delicious way to protect against inflammation. In addition, you can enjoy green tea or an occasional glass of red wine, both natural antioxidants. These are both better choices than sweetened beverages like colas that can increase inflammation. Getting enough sleep is also important because this is the time when your body performs critical repairs of cell damage that have occurred throughout the day. Last, taking the time to de-stress through yoga and meditation will help lower inflammation levels while improving your outlook on life.

Healthy eating and positive habits are important in reducing inflammation. However, inflammation does not have to negatively affect your health, even if you don’t always maintain the healthiest diet. According to a recent study, a substance found in grapes called  resveratrol can help to reduce or even eliminate the effects of eating an unhealthy diet. Monkeys who are fed a high-fat and high-sugar diet tend to have muscles that become fatigued quickly. Adding a resveratrol supplement to their otherwise unhealthy diet led to less fatigue and inflammation in the muscles, partially compensating for the cost of a poor diet. This indicates that one of the health benefits of resveratrol may be that little “cheats” don’t have as large of an effect on your tissues, including the delicate tissues in your heart.

The health benefits of resveratrol may be just what someone people need to withstand the negative effects of modern life. While it’s important to try to eat healthily and lower your risk of inflammation through lifestyle changes, supplementing with this grape derivative can help you to get the boost you need to feel and be healthier over your lifetime.

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Filed Under: Cellular Health, Heart Health, Men's Health, Women's Health

Vitamin D and Asthma: Supplementation Found to Lower Risk of Severe Attacks

Oct 10 by Ewcopywriting Leave a Comment

Most of us take breathing for granted. While everyone must breathe to stay alive, it happens unconsciously and we only notice it when we have a cold or another illness that makes breathing difficult. Asthma is a health problem affecting millions of people in the United States alone. While there are medications available, many people with asthma still suffer from debilitating symptoms and even have to seek emergency medical care just to stay alive. New research on vitamin D and asthma suggests that taking this supplement along with your current medications can reduce your daily symptoms, your number of asthma attacks and the amount of rescue medication that you need to breathe.

The Physiology of Asthma

Although many people have asthma, it is often misunderstood. Asthma is not a minor disease, but rather one that can lower your quality of life and even cause death when left untreated. Asthma is a disease affecting the passages that carry air to your lungs. Asthmatic people have airways that are prone to inflammation, which can reduce the amount of air that both enters and exits the lungs. Many asthmatics have low level chronic inflammation, but also sometimes experience an asthma attack. In an asthma attack, the inflammation increases quickly and compromises the ability to breathe. In many cases, this can be life-threatening.

The symptoms of asthma are primarily caused by inflammation of the airway passages. Symptoms include wheezing, shortness of breath and coughing. Some people can identify triggers that cause an asthma attack to happen, such as seasonal allergies, dust, or aerobic exercise. Although the risk of having an asthma attack is 100 times greater during the night, for many asthma sufferers, the attacks appear to happen randomly. While treatment regimens vary for each unique individual, they usually include daily medication to reduce chronic inflammation as well as rescue inhalers that can be used when an attack is beginning. When these medications fail, steroids are used to immediately open airways. While many people can manage their disease effectively with modern medicines, others struggle with symptoms regularly and live in fear of a deadly attack.

Vitamin D and Asthma Attacks

Vitamin D and Asthma: Supplementation Found to Lower Risk of Severe AttacksBecause asthma can be difficult to manage effectively and the medications have intense side effects, many people are searching for natural remedies to help them breathe easily. New research on vitamin D and asthma suggests that this vitamin may help to prevent severe attacks. People who add vitamin D to their current asthma treatment regimen may see their number of attacks reduced by half. Six percent of people in this study using just their standard medications had to get medical care for an attack while three percent of the group that took additional vitamin D required this help. In addition, people taking vitamin D needed steroids less often.

How can vitamin D make such a difference in the number of asthma attacks? The exact mechanism remains unclear, but previous studies have found that vitamin D deficiencies are linked to worse asthma symptoms. It is possible that many asthma sufferers are suffering from a vitamin deficiency that worsens their symptoms, which is easily treated. Researchers noted that it is not clear whether vitamin D supplements will reduce attacks in people who already have high levels of this vitamin in their bodies.

Natural Approaches to Treating Asthma

Because asthma is difficult to treat even with the best modern medication regimen, many people are turning to natural remedies to improve their breathing. Antioxidants such as vitamin C and vitamin E may help by reducing overall inflammation levels in your body. Caffeine can help some asthma sufferers, as it dilates air passages. While some of these supplements may be effective, every asthma sufferer is different and has a treatment plan tailored to their needs. It is important to talk to your physician before adding a new treatment to your current plan.

A variety of modern studies are finding that chronic diseases, even potentially deadly ones like asthma, can be effectively treated with safe and natural remedies. Vitamins and minerals are essential to our health, so supplements can often make a huge difference. Getting a wide variety of essential vitamins may be a breath of relief for many asthma sufferers.

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Filed Under: Chronobiology, Chronotherapy, Men's Health, Women's Health

Ten Effective Natural Supplements for Andropause

Oct 07 by Ewcopywriting Leave a Comment

Most people have heard of menopause, the time at the end of a woman’s reproductive life during which hormone levels dip considerably. However, many don’t realize that men undergo a similar process. As men age, levels of androgens (male hormones) decrease, often contributing to a variety of health problems. This time period is called andropause, but is also known as men’s change of life or “manopause.” In addition, during this time many men deal with physical changes such as hyperplasia in their prostate and other new health concerns.

The effects of gradually-decreasing levels of testosterone and other male hormones can affect almost every part of your health and your life. Men often report a lower libido, fatigue, depression and weight gain. In addition, they may experience more subtle effects such as a higher risk of diabetes. Unlike menopause, andropause happens slowly and subtly over decades, which means many men never realize that they are going through it and don’t seek out the treatment that they need.  The good news is there are many natural ingredients and supplements for andropause that can support your body in optimal health as you go through this natural transition.

Changing Needs Over a Lifetime

From birth through old age, our bodies are constantly changing and undergoing different processes. As a result, we have unique health needs in each stage of life. For example, infants need a diet rich in fats and cholesterol to support rapid growth in their brains. Children have higher calcium needs because their bones are growing quickly. Gender also plays a role; women of childbearing age need extra folic acid because this is so important to fetal development.

Like all people, men in andropause and beyond have a special set of health needs. They benefit from B vitamins to provide energy, vitamins E and C which function as healthy building blocks and other natural ingredients that can support healthy androgen levels without harming their prostate or their heart. While this may seem like a tall order, there are a variety of natural supplements for andropause that promote good health in aging men.

Supplements for Andropause

Our bodies are designed to experience declining levels of sex hormones as we age and our fertile years wane. However, there are several supplements for andropause that can offer support during this adjustment. These include:

L-arginine

L-arginine is a natural amino acid that encourages healthy blood flow and supports cardiovascular health. It accomplishes this by supporting healthy levels of nitric oxide, a natural blood vessel and muscle relaxant.

L-taurine

This amino acid functions in the human body as a “membrane stabilizer.” L-taurine has been found to help maintain muscle strength and proper nerve transmission.

Saw Palmetto

Ten Effective Natural Supplements for Andropause 1Saw palmetto has been found to help protect against prostate problems that often occur as men age. Benign prostatic hyperplasia (BPH) is one of the most common health problems in older men and can cause a variety of unpleasant symptoms such as urinary retention and frequent urination.

Ginkgo Biloba

Ginkgo promotes normal cognitive function, supporting healthy memory and attention span. These are both major concerns for many aging men.

Lignans

Lignans are a class of plant phenols that act as powerful antioxidants in the human body. Supplying the body with sufficient levels of antioxidants can help protect against some of the deleterious effects of aging and specifically support cardiovascular and cellular health.

Tribulus Terrestris

Tribulus is a derivative of the terrestris or puncture vine plant that works to naturally support healthy testosterone levels in men.

Piperine

Piperine is a black pepper derivative that has been found to have a wide range of health benefits, including helping to soothe minor pain.

B Vitamins

B vitamins act as vital co-factors to help boost energy and support a healthy metabolism.

Vitamin E

Vitamin E is a powerful antioxidant vitamin that helps your body to resist the biochemical stressors it encounters on a daily basis over the years.

Vitamin C

Ten Effective Natural Supplements for AndropauseVitamin C is an essential vitamin for the creation and repair of connective tissue. The breakdown of connective tissue and the collagen that supports it is the main culprit behind wrinkles and other visible signs of aging.

There are many natural, affordable and side-effect free supplements that can help you to age more gracefully and enjoy better health along the way. If or someone you love is a man approaching the golden years, research supplements for andropause and the difference that these can make in your quality of life.

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Filed Under: Andropause, Chronobiology, Men's Health, Prostate Health

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